Interferon-Gamma release assay and tuberculin skin test: same purpose different problems
نویسندگان
چکیده
منابع مشابه
Performance of Tuberculin Skin Test Measured against Interferon Gamma Release Assay as Reference Standard in Children
Objectives. International guidelines differ in the threshold of tuberculin skin test (TST) induration regarded as indicating Mycobacterium (M.) tuberculosis infection. Interferon gamma release assay (IGRA) results were used as reference to assess performance of TST induration thresholds for detection of M. tuberculosis infection in children. Design. Systematic review which included studies cont...
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BACKGROUND Identifying latent tuberculosis infection (LTBI) in people migrating from TB endemic regions to low incidence countries is an important control measure. However, no prospective longitudinal comparisons between diagnostic tests used in such migrant populations are available. OBJECTIVES To compare commercial interferon (IFN)-gamma release assays (IGRAs) and the tuberculin skin test (...
متن کاملInterferon-gamma-release assays: Better than tuberculin skin testing?
Although the tuberculin skin test has long been the standard for detecting latent tuberculosis infection, it has many limitations. Interferon-gamma-release assays are gaining acceptance as an alternative. In this paper we present cases to illustrate how these new tests can be used and how to interpret the results.
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BACKGROUND AND OBJECTIVES Patients in ESRD on hemodialysis with latent tuberculosis (TB) infection have 10 to 25 times the risk of reactivation into active disease compared with healthy adults. This study investigates the prevalence of latent TB infection in dialysis patients from a country with an intermediate burden of TB and its associated risk factors using the QuantiFERON-TB Gold in-tube t...
متن کاملInterferon-gamma release assay agreement with tuberculin skin test in pretransplant screening for latent tuberculosis in a high-prevalence country.
INTRODUCTION Tuberculosis reactivation is one of significant complications after transplantation. Tuberculin skin test (TST) has been the major available screening test in end-stage renal disease patients, but it is associated with a low accuracy. Recently, an interferon-gamma release assay (IGRA) has been approved as a substitution test in diagnosis of Mycobacterium tuberculosis infection. Thi...
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ژورنال
عنوان ژورنال: European Journal of Public Health
سال: 2018
ISSN: 1101-1262,1464-360X
DOI: 10.1093/eurpub/cky218.141